Heartburn can come on unexpectedly after eating a big meal, eating too fast or when you're feeling stressed out. Be prepared with antacid liquids. Liquid antacids help to neutralize acid in your stomach so that it causes less irritation to your digestive tract. Doctors and pharmacists often recommend antacids for relief of occasional heartburn and indigestion. Antacids in liquid form are easy to take and provide quick relief of burning and stomach irritation. Be sure to ask your doctor about your symptoms before taking over-the-counter medication.